If you mean can you play a combo (say, three 3s) plus an ace, then no; animal companions can’t be added to combos – you can only add them to a single other card.
If you mean can you play a combo consisting of aces, then officially that’s also a no, unless it’s a ‘combo’ of only two aces (a.k.a. adding an animal companion to another ace card), or if you have special dispensation : )